She was arrested on 7 October 2005 just before leaving to Dublin where she was due to attend an international conference on human rights protection.
She was convicted on 13 counts and sentenced to 8 years in prison for criticizing the Uzbek government for having used violence against the participants of the peaceful demonstration in Andijan in 2005.
For the 60th anniversary of the Universal Declaration of Human Rights, the "Fiery Hearts Club" was awarded with the French Republic's "Liberty, Equality, Fraternity" Prize.
At present she is at the head of the International Human Rights Organization "Fiery Hearts", registered and based in Paris.
Although Tojiboyeva was not eyewitness of those events, her mother's memories played a significant role in her maturing as a human rights defender.
At the same time, on a voluntary basis, Tojiboyeva was in charge of the complaint department and the press centre of the institution in question.
Tojiboyeva started to declaim against the executives abusing their authority and rights of simple citizens in the central and local press.
She pursued bringing to the agenda the passage of the law concerning the organization of public control of the legislative acts implementation.
In January 2002, at the plenary session of the municipal council of Margilan two-year activity of the "Fiery Hearts Club" was discussed.
Subsequently, articles, feature stories, special reports about the club's activity were issued in the local and republican media.
On June 30, 2002, Tojiboyeva together with Scott Peterson, a correspondent of the international newspaper "Christian Science Monitor", visited Durmen village, where Mamadaliev's family lived.
The next day Tojiboyeva was accused in breaching the articles "Failure to obey order or regulation issued by a police officer" and "Disorderly conduct".
Due to the lack of accusatory documents presented to the court as well as Tojiboyeva's claims to arrange medico-legal assessment, the case was transferred to the Public Prosecutor's Office and she was released from the courtroom.
On September 5, 2002, the Criminal Court of Fergana region recognized illegal the actions of Kirgulijsky district officers.
Due to that event, the "Fiery Hearts Club" and its leader gained even higher authority among people and that caused the increase in their activity.
The Prosecutor General's Office executive Bakhadyr Pulatov came to Ferghana region to check the arguments of the demand and met Tojiboyeva.
After making sure the case had been faked-up against the planned demonstration, Tojiboyeva decided not to present herself in the court and hid in Durmen.
Then she called to the Internal Affairs Department of Ferghana region and expressed her will to succumb to the authorities in return of abatement of persecution and pressure.
At the beginning of December 2003, one of high officials of the Internal Affairs Department of Ferghana region called Tojiboyeva in sozzled state and told her that she would be punished for her actions and that her days had been already numbered.
On April 4, 2005, Tojiboyeva sent a telegram to the President of the Republic of Uzbekistan Islam Karimov on behalf of the "Fiery Hearts Club" expounding a difficult socio-political situation in Andijan region.
On April 15, 2005, in the Ministry of Internal of the Republic of Uzbekistan there was held a press conference concerning published under the pseudonym of the political scientist Safar Abdulaev.
Back to Tojiboyeva got under medical treatment in a local hospital, however she didn't turn to anybody concerning the violences and tortures that she had undergone.
That was because the high official that was in charge of Tojiboyeva's detention as well as mockery at her, told her to keep silence, otherwise he threatened to make her daughter experience the same adventure as hers.
During the legal proceedings concerning the Andijan events initiated on September 20, 2005, the Deputy Solicitor General of the Republic accused Tojiboyeva of anti-government activity under the false name of a human rights activist.
However, on October 7, 2005, Tojiboyeva was arrested by security officers of the Ministry of Interior of Uzbekistan on a charge of deceptive practices.
Despite the fact that only Tojiboyeva in person was incriminated, the members of the "Fiery Hearts Club" were searched as well, besides all the documents and materials (videotapes, audio cassettes, etc.)