He is known for his directorial debut film Cairo 678 (Les Femmes du bus 678),[2] which was released a month before the Egyptian revolution, and for directing Disney's Marvel series Moon Knight.

The film follows the intertwining stories of a vigilante trio of women who take on the sexual harassment epidemic in Cairo.

The film was distributed internationally and fared well notably in France, where it sold 265,000 tickets and received ÉcranTotal's "coup de foudre du public" audience recognition award.

[4] In October 2020 Diab was hired to direct episodes of Disney+ streaming series Moon Knight, set in the Marvel Cinematic Universe.

Attention to the smallest details was important to him, such as adding purple hues and the vibrant atmosphere of the Nile River at night.