[7] Mohamed Ennaceur earned a diploma from the Institut des Hautes Études de Tunis and a doctorate in social law from the University of Paris 1 Pantheon-Sorbonne.

He was Commissioner-General of the Office for Tunisian Workers Overseas (1973–74), chaired the World Employment Conference (1976) and the Arab League Social Affairs Bureau (1980–83).

Between 1991 and 1996 he went on to serve as coordinator of the African group in the World Trade Organization and led the Tunisian permanent mission to the United Nations in Geneva.

[10] On 31 December, after Béji Caïd Essebsi became President of the Republic, he succeeded him as interim head of the Nidaa Tounes party.

[14] In late July 2019, shortly after the death of his predecessor, Beji Caid Essebsi, Ennaceur was reported to be in poor health.