Mohammad-Reza Khatami (Persian: محمدرضا خاتمی, born 1958) is an Iranian reformist politician and nephrologist.

[1] Khatami is educated in medicine and before entering politics, he was a practicing nephrologist (kidney specialist) for a number of years.

Khatami was the first Secretary-General of the Islamic Iran Participation Front, the largest Iranian reformist party.

"[2] In 1983, at the young age of 25, Khatami married Zahra Eshraghi, a granddaughter of Ruhollah Khomeini (founder of the Islamic republic) and an activist in women's rights.

On 28 March 2020, Khatami announced he tests positive for COVID-19 with publishing a video showing he is at hospital.