He attended All Saints High School and graduated from Nizam College, Osmania University with a Bachelor of Commerce degree.

[7] After Azharuddin's rumored affairs with multiple people, notably badminton player Jwala Gutta, Sangeeta filed for a divorce in 2010.

[20][21] He led the team to victory in 14 tests and 90 ODIs, both records until surpassed by Sourav Ganguly and MS Dhoni respectively.

[23] Though India lost the match, former England cricketer Vic Marks called it "the most dazzling Test century" he had ever witnessed, in his column for The Observer.

[26][27] Azharuddin led India to victory in the 1990–91 Asia Cup beating Sri Lanka in the final.

[33] During the second test of South Africa's India tour in 1996–97 at Kolkata, Azharuddin scored a century off 74 deliveries equaling Kapil Dev's record for the fastest test century by an India player and fourth overall, in terms of balls faced.

[36] He was named the man of the match and the series after aggregating 388 runs at an average of 77.60[37][38] Azharuddin scored seven centuries in ODIs with a best of 153 coming against Zimbabwe on 9 April 1998 in Cuttack.

[40] Azharuddin played the final match of his international career in an ODI against Pakistan on 3 June 2000 in the 2000 Asia Cup.

[44] International Cricket Council and BCCI banned Azharuddin for life based on a report by Central Bureau of Investigation.

[7] Mike Atherton and Angus Fraser said Azharuddin's "genius was second only to Brian Lara among batsmen of their generation.

"[24] Predominantly a middle order batsman, Azharuddin played 99 test matches for India and scored 6,215 runs at an average of 45.03, including 22 centuries and 21 half-centuries.

[53] He contested the 2014 Indian general election from Tonk–Sawai Madhopur in Rajasthan but lost to Sukhbir Singh Jaunapuria of Bharatiya Janata Party.

[60] Azharuddin has also received doctorate degree (honoris causa) from Jamia Hamdard, New Delhi on 21 September 2023.

depicting the investigations and allegations of match fixing against former cricketers including Mohammad Azharuddin premiered on 17 March 2023.