Mohammad Ismail Abdul Khalique is an Islamic scholar and an Indian politician from Malegaon city, Maharashtra.

He won from the Malegaon Central (Vidhan Sabha constituency).

In 2014, he joined Nationalist Congress Party and contested elections, but lost.

He began his political career as a member of the Jan Surajya Shakti party, serving as an MLA from the Malegaon Central Assembly constituency in Maharashtra from 2009 to 2014.

In 2019, Khalique transitioned to the All India Majlis-e-Ittehadul Muslimeen (AIMIM) and contested the 2019 Maharashtra Legislative Assembly election from the Malegaon Central Assembly constituency.