Mohammed Sani Sami was Governor of Bauchi State, Nigeria from January 1984 to August 1985 during the military regime of Major General Muhammadu Buhari.

He attended the Mons Officer Cadet School, Aldershot (United Kingdom), and was commissioned on July 25, 1963.

General Murtala Muhammed, head of state from July 1975 to February 1976, appointed Lieutenant Colonel Sani Sami commander of the Brigade of Guards.

[2] Mohammed Sani Sami was appointed governor of Bauchi State after a coup on 31 December 1983 that brought General Muhammadu Buhari to power.

He upgraded medical facilities, and undertook a major agricultural development program named "back to land".