His father, Mohammed ben Khalifa Fikini, was one of the leaders of resistance against the Italian invasion of Libya in 1911.
The title of his thesis was "Le règlement de la question libyenne par l'Organisation des Nations Unies".
In March 1963, King Idris I of Libya assigned Fikini to form a new cabinet, in which he also became foreign minister.
This led to a disagreement with the commander of the security force Mahmud Buguaitin who defended his officers (though he had not ordered them to shoot the demonstrators).
The most recent information about him that he met the Libyan leader Muammar Gaddafi in 1982 along with many officials from the Kingdom era.