On 8 March 2014, the detachment in coordination with Moldovan border guard discovered and seized 6 canisters with 165 litres of alcohol.

A guardsman of the detachment (Volodymyr Oleksiyovych Blazhko) was killed on 27 July 2014 during the Battle of the Border.

[5] The deputy commander of Mohylev-Podilskyi border detachment (Semenov Vyacheslav Anatoliyovych) was killed in combat on 17 February 2015, when separatists reinforced by artillery and tanks, attacked the Fashchivka checkpoint near Debaltseve.

[9] On 1 November 2022 near Nevelske, a Guardsman of the Detachment (Strelkov Georgy Mykolayovych) was killed during Russian artillery fire while saving his comrades[10] and was posthumously awarded the Hero of Ukraine.

[12] In August 2024, the detachment detained a Moldovan man who drunkenly crossed the border on a bet.