The spokesman of Foreign Affairs Department of the Popular Party, Javier Rupérez, headed the Spanish delegation of the Parliamentary Assembly of the Organization for Security and Co-operation in Europe on 23 February 1994 to Chişinău to observe the development of the first democratic elections in Moldova.

In the same date the then Spanish president, Felipe González, sent a letter to the Moldovan Government explaining the benefits that the entrance in the "Association for Peace" of NATO would suppose for Moldova.

[7] On 6 November 2000 the Secretary of State for European Affairs, Ramon de Miguel, traveled to Moldova to carry out a visit of work of two days during which he analyzed the bilateral relations with the president of the Republic, Petru Lucinschi, and with prime minister, Dumitru Braghis.

Miguel also met with the Deputy Prime-Minister for Defense Affairs, Valeriu Cosarciuc, the Minister of Exteriors, Nicolae Tabacuru and the Vice-Minister, Iurie Leanca, as well as with the President of the Commission for Transnistria Vasile Sturza, a group of Spanish industrialists and several members of the Moldovan Parliament.

[8] In October 2005, the new ambassador of Spain in Bucharest, Juan Pablo Garci'a-Berdoy, visited Chişinău to offer credentials and he met with the Vice-Minister of Foreign Affairs, Eugenia Kistruga.

[13] Sánchez announced the plan to open a diplomatic office in Chişinău, and told Sandu Spain's position defending "the sovereignty and territorial integrity" of Moldova "within its internationally recognized borders".

[14] Minister Plenipotentiary Juan Antonio Martin Burgos was appointed and acredited as Chargé d'Affaires a.i., Head of the Diplomatic Office of the Kingdom of Spain in Chisinau in June 2022.