Moniaive (/mɒniˈaɪv/ 'monny-IVE'; Scottish Gaelic: Am Moine Naomh, "The Holy Moor") is a village in the Parish of Glencairn, in Dumfries and Galloway, southwest Scotland.

On 4 July 1636 King Charles I granted a charter in favour of William, Earl of Dumfries, making Moniaive a 'free Burgh of Barony'.

The Scottish artist James Paterson, a founder member of 'The Glasgow Boys', settled in Moniaive in 1884 and stayed for 22 years.

He painted many local scenes including "The Last Turning" – a view of a woman approaching the village on the lane on the western side of the old millpond (now drained) in the Dalwhat Valley – now displayed in the Kelvingrove Art Gallery and Museum.

A James Paterson museum existed within the village until 2005 displaying photographs and memorabilia from the collection of his granddaughter, Anne Paterson-Wallace.

The area has a large self-employed community including writers, artists, graphic designers, historical interpretation services, clothing designers, aromatherapists, stained glass workers, a wine importing business, a chocolatier, computer repairs, garden and landscaping services, plant nursery, and child care.