[1] In 2002, Gruber gained her first experience as a cabaret artist in the comedy series Kanal fatal (in German), in which she portrayed Kellnerin Monique, a typical Bavarian waitress who, in broad vernacular speech, talks about her adventures in gastronomy.

[1] She reported from Oktoberfest in Munich for Bayerischer Rundfunk or BR ('Bavarian Broadcasting') in 2004, and in 2006 she was a celebrity gossip commentator for Grünwald Freitagscomedy.

[4] From January 2011 to the end of 2013, Gruber, along with Bruno Jonas and Rick Kavanian, was a core member of Die Klugscheißer, a monthly satirical TV series of Bavarian Television.

From 2008 to 2011, she played the leading role of Hannelore Herbst in the Bavarian Television series Der Kaiser von Schexing.

[9][10] At the same time, she also played Moni Riemerschmidt in the new Heiter bis tödlich episodes of the Bavarian police series München 7 along with Florian Karlheim, Andreas Giebel, and Christine Neubauer.

[1] In the turn of the year 2012–13, Gruber performed with Michael Niavarani in their "patchwork program" called Best of Beide, in a repeatedly sold-out town hall in Vienna.

[15][failed verification] On June 10, 2023 Gruber spoke on a demonstration against the climate policy of the German government, in particular against the planned update of a law regulating heating of buildings (Gebäudeenergiegesetz),[16] mobilizing 13,000 opponents.