Starting from the south, it links the Puerta del Sol and the so-called Red de San Luis (the junction with the Gran Vía).

All its path falls within the limits of the Sol neighborhood, in turn part of the Centro District of the Spanish capital.

The writer Valle Inclán set in 1920 an scene of his play Bohemian Lights in the street; the place where the "taberna Pica Lagartos" was located.

[7] The Church of San Luis Obispo suffered a fire in March 1936 that led to its destruction, with the complete demolition taking place in 1943.

[12] In August 2018 works towards the creation of a pedestrian underground connection between the Metro stations of Sol and Gran Vía passing below the street started.