Moon-Boy made his debut in Devil Dinosaur #1 (April 1978) and was a continuing character in all nine issues of the series' run.

Kirby's intent was for the duo to be inhabitants of Earth's prehistoric past as evidenced by a title on the cover of Devil Dinosaur #1 which proclaims Moon-Boy to be the "first human".

[2] Moon-Boy was born into a tribe of ape-like humanoids known as the "Small-Folk" in the "Valley of Flame", a region of numerous active volcanoes.

[7] After several trips to the modern era of Earth-616 via magic, time travel, and teleportation by mutants, the pair eventually settle in the Savage Land of Earth-616.

[8] After the Roxxon Energy Corporation invades the Savage Land, Ka-Zar recruits Moon-Boy and Devil Dinosaur to fight them.

However, Moon-Boy is killed while a temporal vortex transports the Killer Folk, Devil Dinosaur, and the Nightstone to New York City.

Moon-Boy appears as a playable character in Lego Marvel's Avengers, voiced again by James Arnold Taylor.