The garden's central landmark is the firetower, which soars to a height of 100 ft (30 m) and was purchased during an auction in Olanta, South Carolina in 2004.

Due to its location in the inner Atlantic coastal plain, the topography of the garden is flat, with a low elevation and little change in relief.

[3] Voucher specimens from plants accessioned at the garden are housed at the A.C. Moore Herbarium (USCH) at the University of South Carolina.

The coastal plain ecosystem is the primary focus of the collection, though the piedmont and mountain regions of the state are represented as well.

A collection considering of plants historically cultivated in the Southeastern United States and considered part of its distinct imagery, including Camellia, Chrysanthemum, Crinum, Magnolia, Quercus virginiana (Southern Live Oak), and Narcissus (particularly the 'Jonquils', or those in Division 7 of the Royal Horticultural Society classification of the group, derived from and showing characteristics of Narcissus Sect.

Though no longer utilized for fire spotting, the tower serves as a trellis for specimens of Taxodium distichum 'Emerald Falls', trained to climb by staff horticulturists.

This region of the garden also exhibits several specimens by local South Carolina topiary artist Pearl Fryar.

The characteristic structure of this area is the Spring House, constructed with timber from a neighboring county, Bamboo (Phyllostachys sp.)

Nearby ponds collect several aquatic and marginal species including Scirpus californicus, Eryngium aquaticum, and Glyptostrobus pensilis.

Current plans involve expansion of the nursery and construction of additional greenhouses, one for vegetable production as well as installation of a trial garden for expanded research.

Moore Farms Botanical Garden is frequently involved in outreach and improvement projects in Lake City, and is often utilized as a site for events in support of these causes.