The Rebecca and John Moores Cancer Center is the region's only NCI-designated Cancer Center, part of UC San Diego Health and affiliated with the University of California, San Diego.

A five-story building, home to the center, was opened in La Jolla in 2005.

[2] The Moores Cancer Center provides outpatient treatment on site.

Inpatient hospital treatment is provided at the adjacent Jacobs Medical Center in the Pauline and Stanley Foster Pavilion for Cancer Care, which opened in 2016 and has three floors dedicated to oncology,[3] and at UC San Diego Medical Center in Hillcrest, which has recently expanded its cancer services.

[4] Lippman was succeeded by Joseph Califano who served in the role from 2022 until early 2023.