The Mor Ephrem Syriac Orthodox Church (Turkish: İstanbul Mor Efrem Süryani Kadim Ortodoks Kilisesi, Syriac: ܥܕܬܐ ܕܡܪܝ ܐܦܪܝܡ ܕܣܘܪ̈ܝܝܐ ܩܕ̈ܡܝܐ ܐܪ̈ܬܕܘܟܣܝܐ, romanized: ʿIdto d-Mor ʾAp̄rem d-Suryoye Qamoye ʾOrṯodoksoye) is a Syriac Orthodox church in Yeşilköy on the European part of Istanbul.

[2] In 2009, then Prime Minister Recep Tayyip Erdoğan ordered the Istanbul Metropolitan Municipality to find space for the building.

[3] The land was allocated by Istanbul Mayor Kadir Topbaş:[4] It is an Italian Latin Catholic cemetery[3] confiscated in 1950 by the Turkish state and unused since 1996.

[5] On 3 August 2019, in the presence of metropolitan bishop of the Istanbul-Syriac Church Yusuf Çetin, of Ecumenical Patriarch of Constantinople Bartholomew I, and of Istanbul Mayor Ekrem İmamoğlu, President Erdoğan laid in Yeşilköy the first stone of church.

[8][9] It was inaugurated on 8 October 2023 by Erdoğan,[10] in presence of Speaker of the Grand National Assembly Numan Kurtulmuş, Minister of Internal Affairs Ali Yerlikaya, Minister of Culture and Tourism Mehmet Nuri Ersoy, Presidential Communications Director Fahrettin Altun, AK Party Spokesperson Ömer Çelik and representatives of religious communities such as Yusuf Çetin, Deputy Patriarch of the Assyrian Orthodox Community and Sait Susin, President of the Istanbul Syriac Kadim Foundation.