Moravský Žižkov is a municipality and village in Břeclav District in the South Moravian Region of the Czech Republic.

It lies mostly in the Lower Morava Valley, The northern part of the municipal territory lies in the Kyjov Hills and includes the highest point of Moravský Žižkov at 260 m (850 ft) above sea level.

Founded in 1731, it is one of the youngest communities of the South Moravian Region.

It was a part of Velké Bílovice until 1792, when it became a sovereign municipality.

The main landmark of Moravský Žižkov is the Church of Our Lady Victorious.