Mordechai Ish-Shalom (Hebrew: מרדכי איש-שלום‎), (1902–1991[1]), was an Israeli politician and labor leader.

Mordechai Ish-Shalom was born in Lithuania during the reign of the Russian Empire.

His labor career began in the Stonecutters' Union in 1935; he then rose through the ranks of the Histadrut, the Israeli trade union congress.

[1] In 1964, Ish-Shalom established an interdisciplinary professional team to plan the modernization of Jerusalem.

[2] In the 1970s, he was instrumental in the development of Kiryat Wolfson, a five-tower high-rise project overlooking Sacher Park.