The chaplains were formerly Carmelite friars resident in the building, but since 2021 priests from York Oratory have been ministering to the chaplaincy.

It is located on Main Street in Heslington, which is towards the south edge of the university's Campus West.

[3] From 1869, the parish of St Paul's Church in Heslington was styled as a vicarage, having previously been a perpetual curacy.

The last vicar to live there sold half of the grounds to himself in 1964 to retire to, where he built Orchard House.

Connections were made beyond spiritual communities, and York Pride felt comfortable to hold events at More House.

[10] In 2021, Oratorians from the Oratory Church of Saint Wilfrid in York were invited to minister to the chaplaincy, with Fr.

[11] More House hosts most meetings of the University of York Catholic Students' Society (CaSSoc), which occur every week during term time on Thursdays.

[12] In October 2022 the CaSSoc St Vincent de Paul group (SVP1833) held a sponsored sleepout in the grounds of More House to raise funds to cover the cost of a campaign to support the homeless in York.