The school is a charter member of the Ohio Valley Conference and has competed in the OVC since its inception in 1948.

Morehead State has made nine NCAA Tournament appearances, with the most recent coming during the 2023–24 season.

The Eagles were most recently coached by Preston Spradlin, who resigned after his eighth season at Morehead State.

He would go on to play the most NBA games by an Eagle, as he logged 478 career appearances over eight seasons with the Nuggets, Houston Rockets, and Brooklyn Nets from 2011–19.

Faried scored 5,430 points and pulled down 3,884 rebounds in the NBA, both are the most by a Morehead State player.