In 1986, she co-founded ISO, a dance company that embodied an approach they called "serious fun" and sometimes collaborated with a singing group, and gave performances around the country and abroad.

She was hired as a choreographer, and subsequently as a belly dancer for the song "Mysterious Ways" during the band's Zoo TV Tour in 1992 and 1993.

[8] At age 16, she spent time at the Interlochen Arts Academy in Michigan and when 17, left with her sister for a year of dancing in Paris.

"[1] There she joined up with Daniel Ezralow, Jamey Hampton, and Ashley Roland, and the four created the Connecticut-based, dancer-illusionist company MOMIX.

With ISO, they set their acro dance moves against the new-wave a cappella singing of The Bobs in combined performances.

[12] In it, director Matt Mahurin portrayed Steinberg in an abstract style, swirling in various positions in shots interposed with the band performing.

[11][12] During a Los Angeles stop on the band's subsequent Joshua Tree Tour, Steinberg met The Edge (actual name Dave Evans) in person for the first time during a party at her house.

[1] She additionally did concert or music video choreographic work for David Bowie, Rod Stewart, Sting, and Lenny Kravitz.

"[17] In one 1990 performance, Steinberg used elastic bands to playfully reshape her arms and legs as noodles, then flew from wires like an angel.

"[19] After meeting U2 in 1987, Steinberg stayed in touch with Bono and when the group was putting the Zoo TV Tour together in 1992, the lead singer thought it would be good to have a choreographer to critique his moves on stage.

[12][21] Recognizing Bono was not a dancer, she focused on movements he could do, and sought to help him pace himself and not get lost visually in the show's enormous stage set.

[20] Bono asked Steinberg if she would like to take over and she agreed, although she had never belly danced before[4] and by her own description did not have the voluptuous body usually associated with the form.

[24] Steinberg was originally reluctant to put her own activities on hold to continue on to the "Zooropa" leg of the tour, but eventually agreed.

[4][30] A review of the film on DVD Talk said that "Moreleigh Steinberg's dance-filled daydream about relationships in freefall will be difficult for some to appreciate (the mostly modern dance is very insular and odd), but the brilliant cinematic mood created by the director helps us over the slightly strange nature of it all.

[33] Since Steinberg settled in Ireland, she has been involved in a number of projects, including doing the lighting for a Royal Hibernian Academy fringe gallery exhibition in 2001 and for Rex Levitates' dance production Bread & Circus in 2007, which showcases her collaborator Liz Roche.

[36] She was the artistic director of the 2010s Dance Homage to Irish painter Louis le Brocquy, entitled Cold Dream Colour.

[34] The music for Cold Dream Colour is composed by The Edge in collaboration with Paul Chavez (known for his experimental electronic compositions under the project name FeltLike).

[38] The US Cold Dream Colour was presented by Arcane Collective,[37] a production company that Steinberg and Oguri had co-founded in Spring 2011.

[39] Steinberg continued to direct and appear in productions of Arcane Collective, including a 2016 performance at New York Live Arts consisting of adaptations of scenes from the Samuel Beckett trilogy.

[40] In 2017, Steinberg was featured as the second of two women in the video accompanying performances of the song "Trip Through Your Wires" on U2's Joshua Tree Tour 2017.

She is dressed as a cowgirl, often drawing stage comment from Bono, while an American flag is painted on a wooden shack by the other woman.

[48] The couple married on 17 June 2002 [7] in a small civil service at the Dublin registry office, and a few days later in a ceremony atop a mountain in the South of France.

[7][49] Four days later, their French wedding was held with 200 or more guests at the hilltop village of Èze overlooking the Côte d'Azur followed by a seaside reception.

[34] After discussion with the family, U2 went forward with its 2005–2006 Vertigo Tour, but changed scheduling and reduced dates to enable The Edge to go home more often.

[34] Along with Bono and his wife Ali Hewson, the couple co-owns a 20-room villa in Èze in the Alpes-Maritimes in the South of France, where they often host other celebrities.

[34] The couple spent five years seeking to gain approval for a large, five-home development atop the Sweetwater Mesa hillside in Malibu, California on land they had bought.