He graduated from Nørre Gymnasium in 1983 and studied at Denmark's Journalist Folk High School (Danish: Danmarks Journalisthøjskole) in 1988.

From 1990 until 2005, Løkkegaard worked for the Danish Broadcasting Corporation where he hosted political and entertainment television programs.

He was a rapporteur and the deputy chairman of the Danish delegation to the Nordic Council and to the Parliamentary Assembly of the Mediterranean.

[6][7] He has since been serving as one of eight vice chairs of the Renew Europe group, under the leadership of chairman Dacian Cioloș.

[10] In addition to his committee assignments, Løkkegaard is part of the Parliament's delegation for relations with Australia and New Zealand.

[11] Løkkegaard is highly involved with issues related to communication on and about the EU, and to the creation of an actual European public sphere.