Mortonville is an unincorporated area and historic hamlet in Chester County, Pennsylvania, United States, situated on the eastern bank of the West Branch Brandywine Creek.

The hamlet was founded between 1767 and 1772 by Thomas Hayes, who erected a grist mill and sawmill where the Strasburg Road crossed the creek, on the east bank.

[2] Sketchley and Elizabeth Morton, a couple from Springfield Township, Delaware County, Pennsylvania, bought the former Worth property on April 1, 1840.

In 1849, he turned the Worth house into the Mortonville Hotel (although he was unable to obtain a tavern license for it, a necessity for serving alcohol) and built a wheelwright shop nearby, on the south side of the road.

Other structures include the ruins of a grist mill, a new restaurant being built on an old foundation, canoe sheds, and an apparently modern covered bridge.