[3] In 1877, Karl Masing [ru], a Russian engineer and educator, founded a realschule in Maly Znamensky Lane,[4] which soon became one of the most progressive vocational schools in Russia.

School 57 has general track classes along with its specialized programs and holds a separate admission process for specialized classes in mathematics, humanities[10] and biology, a joint project[11] of the school and the Faculty of Bioengineering and Bioinformatics [ru] of Moscow State University.

[13] School 57 launches two math classes each year, with four- and three-year curriculums, each admitting around 20–25 students who have demonstrated the best problem-solving abilities during the application process.

[3] Students in the specialized classes receive extensive training in their areas of expertise, often covering college-level material in their junior and senior years.

Best specialists in STEM subjects are working with students from 8th to 11th grade in order to make them able to win All-Russian Olimpiad of schoolchildren.

Teaching the specialized math classes isn't limited to faculty staff – additional instructors, many of whom are volunteering alumni, are involved in order to give every student necessary attention.

[26] School 57 offers a number of free courses for middle schoolers preparing students who intend to apply to the mathematics, humanities and biology classes.

[27] The math program includes weekly problem solving sets for sixth-, seventh- and eighth-graders, some of the courses are published.

Class vacations, including those involving intense work (lectures, presentations, field trips), are popular in the school, though not mandated by the administration.

The competition consists of two rounds and a series of lectures on various subjects by school teachers and alumni professors.

The topics covered in the camp's course include the Young tableau, knot invariants and Schubert polynomials.

[35] Lectures take place in all three buildings of the school, the speakers include Alexander Barulin [ru] and Anatoly Starostin.