[5] In February 1936, the cornerstone was laid for Kiryat Avoda, a Modernist building complex designed by architect Joseph Neufeld to solve the shortage of housing for municipal workers.

[6] In the early months of the 1948 Arab–Israeli War, Holon was on the front line, with constant shooting taking place on the border with the village of Tel al-Rish to its northwest—a suburb of Arab Jaffa—and clashes also in the direction of the town of Yazur to the east.

An attack by the Holon-based Haganah militia units on Tel A-Rish was repulsed with considerable losses.

In February 2001, a Palestinian attack at a crowded bus stop in Holon killed eight Israelis and injured twenty-five.

[8] Historic landmarks in Holon slated for preservation include Derech Habitachon ("Safe Road"), paved during the 1948 Arab-Israeli War; water towers in the Moledet and Azor neighborhoods; Hosmasa, a building used by the Haganah; the pillbox guard post; Stroma Square, Mansbach health clinic, Hameshakem building, the Agrobank neighborhood and two schools – Bialik and Shenkar.

A French urban planner was commissioned to design a north-south boulevard with pedestrian walks, bicycle paths, sports fields, parks and waterfalls.

[16] Holon also plays host each year to a street carnival in celebration of the Jewish holiday of Purim, the Adloyada.

[24] Holon is one of only two cities in the world to have a Samaritan community, the other being the village of Kiryat Luza on Mount Gerizim above Nablus on the West Bank.