Mosibudi Mangena OLS (born 7 August 1947 in Tzaneen, Transvaal)[1] is a South Africa politician, former President of the Azanian People's Organisation (AZAPO).

[2] He was born in Tzaneen, matriculated from Hebron Training College in 1969 and achieved an MSc degree in Applied Mathematics from the University of South Africa (called the University of Azania on the AZAPO website).

He is also the former commander in chief of the Azanian National Liberation Army (AZANLA), the former armed wing of AZAPO.

Mangena returned from exile in 1994 and became leader of AZAPO.

After the resignation of Thabo Mbeki as President of South Africa in September 2008, AZAPO announced that they withdrew Mosibudi from his ministerial position.