Mosnac-Saint-Simeux (French pronunciation: [monak sɛ̃ simø]) is a commune in the Charente department in southwestern France.

It was established on 1 January 2021 from the amalgamation of the communes of Mosnac and Saint-Simeux.

[3] The municipal council at its creation was composed of all municipal councillors from both regrouped communes.

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