With the Mospyne railway station [uk], the city serves as a junction for freight and passenger trains.

[citation needed] The city is recorded as being established in 1800, with a settlement called Ust-Ocheretynsk appearing in the areas of Mospyne that year.

At some year after, the landowner Tuzlov settled here and founded the settlement of Tuzlivka, which was later merged with Ust-Ocheretynsk to form the village Makhorivka.

Beginning in the second half of the 19th century, it was part of the Stepanivka-Krynivka volost of Taganroz district [uk], Don Army region.

Railroad tracks were also built to assist the growing coal industry, with the notable financial support of entrepreneurs Mospin, Shabalov, and Utkin.

[citation needed] On 13 May 1919, Andrei Shkuro's Volunteer Army battled with the Makhnovshchina for control of Mospyne, resulting in the White movement capturing the city and the Makhnovists being driven back.

[citation needed] During the War in Donbas, on 30 July 2014, Ukrainian forces killed more than 50 separatists in the city as part of reconnaissance operations.

[citation needed] On 18 July 2020, the enactment of major administrative reform laws removed Mospyne's city of regional significance designation and merged it into the newly expanded Donetsk Raion (district).

Due to the then-ongoing Donbas War and occupation of the city and surrounding areas by the separatist forces of the Donetsk People's Republic (DPR), the new administrative subdivisions remained de jure and the city's DPR government continued to maintain the pre-reform administrative designations and divisions.

The exact ethnic composition in 2001 was as follows:[10] Native language as of the Ukrainian Census of 2001:[2][citation needed] In the mid-1970s, there were six schools in the city, with 166 teachers and 2,853 students.

The Mospinsky mechanical repair plant, established in 1946, operates a foundry, forging and other production facilities.

The plant serves enrichment plants in Donetsk, Luhansk and Dnipropetrovsk oblasts and manufactures over 2,000 various mechanical items, including dredgers, scraper winches, pumps, mine machinery, welded pipes, battery dust collectors, blowers, jigging machines, centrifuges, belt conveyors, locking valves, hydrocyclones, and heaters.

The plant applies a coating composed of monolithic polycrystalline silicon carbide on manufactured items to significantly increase their wear resistance.