The Mosque-Madrasa of al-Asifyah (Arabic: مدرسة الآصفية) is a complex of mosque and madrasa located near the riverbank of Tigris, in Baghdad, Iraq.

The mosque and its associated complex including school buildings, old courts and other former government buildings, and a palace are contained within a 7.57-hectare (18.7-acre) site alongside the banks of the Tigris that forms part of a tentative UNESCO World Heritage Site list.

[1] The mosque complex also includes a small shrine, which is believed to entomb the remains of Islamic scholar al-Kulayni.

The complex originally consisted of a mosque, Sufi lodge named "Dar al-Qu'ran" and khan, and was called Mawla-Khana in lineage to Darwish Mawlai who established the two institutions.

The complex was then taken over by one of the students of the lodge who belonged to the Sufi tariqa, until the building was renovated by Muhammad Jalabi Khatib al-Diwani in 1596.

[1] During the time, two madrasas were built for elementary and secondary levels, attached with preaching area and a minaret.