Moss Bluff is a census-designated place (CDP) in Calcasieu Parish, Louisiana, United States.

Several efforts have been made to incorporate Moss Bluff, but at the present time the community is unincorporated.

As of the 2020 United States census, there were 12,522 people, 4,163 households, and 3,061 families residing in the CDP.

15.5% of all households were made up of individuals, and 5.3% had someone living alone who was 65 years of age or older.

[citation needed] Clifford Joseph Trahan, better known as Johnny Rebel, musician[5] Moss Bluff's elementary and middle schools maintain some of the highest student populations in Calcasieu Parish.