[2] Madu signed with the Hamilton Tiger-Cats of the Canadian Football League in time for the 2014 CFL season.

In his first season in the CFL Madu was dressed for 15 games, carrying the ball 75 times for 348 yards with 2 touchdowns.

[3] Following an injury to starting running back William Powell the Ottawa Redblacks signed Mossis Madu.

[4] When Travon Van also went down with injuries Mossis Madu became the new starting running back for the Redblacks.

[6] Madu was limited by injury to the final two games of the year, where he rushed for 104 yards and a score on 25 carries.