Mother Cabrini High School (MCHS) was a Catholic high school located at 701 Fort Washington Avenue between Fort Tryon Park and West 190th Street, with a facade on Cabrini Boulevard, in the Hudson Heights neighborhood of Washington Heights in Upper Manhattan, New York City.

It offered specialized and distinctive programs of study to enhance the education of its students, all female.

Through much of its history, the student body was largely the children of Irish and Italian immigrants, but by the time of its closure in 2014, the school was predominantly Latino, primarily from the Dominican Republic.

"[4] A post on the website elaborated, saying that the school's deficit had reached "unsustainable levels", despite a projected increase in enrollment and rental income.

The deficit was blamed on: the economic downturn of the past five years ... declining enrollment, managing the growing maintenance expenses of an aging facility, absorbing the cost of unfunded scholarships and tuition assistance, confronting the rising cost of insurance, compensating for the financial vacuum created by the withdrawal of federal grants, and coping with the expanding price tag of running a school and its programs...[9]Some of the school's alumni and parents of current students said they would try to save the school, but the Board believed that the deficit was insurmountable.