Mount Holly Cotton Mill, also known as Alsace Manufacturing Co., is a historic cotton mill complex located at Mount Holly, Gaston County, North Carolina.

The original section was built in 1875, and is a 3 story, rectangular brick mill building with Industrial Italianate detailing.

A three-story addition was built in 1916, and a one-story, T-plan brick machine shop and boiler house was added in 1919.

The complex was converted into a research unit in 1953, and in 1973 was sold to an independent mill operator who presently uses the building for a variety of industrial and commercial purposes.

[1] This article about a property in Gaston County, North Carolina on the National Register of Historic Places is a stub.