The Royal Flying Doctor Service has one of its nine Queensland bases at Mount Isa Airport.

[7] In 2019, the airport was a base for relief efforts for the North West Queensland floods.

It has one runway designated 16/34 with an asphalt surface measuring 2,560 m × 45 m (8,399 ft × 148 ft) and is 3.4 nautical miles (6.3 km; 3.9 mi) north of the city[2] Mount Isa Airport was ranked 30th in Australia for the number of revenue passengers served in financial year 2010–2011.

[1][7] On 22 September 1966 a Vickers Viscount aircraft departed from Mount Isa Airport with twenty passengers for a flight to Brisbane via Longreach.

The crew were unable to extinguish the fire or feather the propeller so made an emergency descent with the intention of landing at Winton, a town 225 NM (417 km; 259 mi) south-east of Mount Isa.