[8] Tyndall lies on the Sierra Crest, which in this region forms the boundary between the John Muir Wilderness and the Inyo National Forest on the east, and Sequoia National Park on the west; and the boundary between Inyo and Tulare counties.

Mount Tyndall was first climbed on July 6, 1864, by Clarence King and Richard Cotter who were members of the California Geological Survey and under the overall direction of Josiah Whitney and the field leadership of William Brewer.

[7] The easiest route on Mount Tyndall in terms of access and climbing is the Northwest Ridge, which involves an easy scramble (class 2).

west of Shepherd Pass and about 1 mile (1.6 km) north of the peak.

Other non-technical routes exist on the gently sloped west side of the peak.