The Big Ten Conference is represented by five schools (Indiana, Oregon, UCLA, USC, Washington).

[1] Due to the Big West addition of men's and women's swimming and diving as a sponsored sport beginning in the 2024-25 school year,[2] six Big West members moved their aquatics programs to their primary conference, including three members (Bakersfield, Cal Poly, and UC Santa Barbara) for whom aquatics comprised their only MPSF teams and thus effectively left the MPSF.

The addition of swimming & diving by the Big West left the MPSF with only two men's and four women's teams in that sport.

The MPSF started a rebuilding process in that sport by announcing on February 13, 2025 that it would add seven members for swimming & diving effective in 2025–26.

At the time of announcement, all were housing swimming & diving in the Western Athletic Conference, which is rumored to be dropping the sport after the 2024–25 season.

Because the WAC dropped football after the 2012 season due to a near-complete membership turnover, it needed to add another men's sport to maintain its Division I status.

[10] In October 2015, Arizona State announced that it would elevate its club team in women's lacrosse to full varsity status starting in the 2017–18 school year (2018 season), which will give the Pac-12 six women's lacrosse schools.

[11] The next major change in conference membership came in January 2016, when the Golden Coast Conference, a water polo-only league that previously operated only a women's competition, announced it would add a men's division effective with the 2016–17 season.

[12] On May 31, 2016, the Big West Conference announced that it would begin sponsoring men's volleyball in the 2017–18 school year (2018 season).

[13] California Baptist also exited the MPSF after dropping its only conference sport of men's volleyball shortly after the 2017 season, and Cal State Bakersfield (now being rebranded athletically as Bakersfield) left the MPSF after dropping its last remaining conference sport of women's water polo at the same time.

[15] It was announced in September 2021 that the MPSF would add women's artistic swimming to the conference as the eleventh sport.

[16] On November 9, 2023, the MPSF announced that it would add beach volleyball, a women-only sport at the NCAA level, for the 2025 season (2024–25 school year).

The inaugural membership in that sport will consist mainly of schools that are leaving the Pac-12 Conference, which sponsors beach volleyball, after 2023–24: California, Oregon, Stanford, UCLA, USC, and Washington.

In June 2023, the Big West announced the addition of men's and women's swimming and diving as a sponsored sport beginning in the 2024-25 school year.

One of the current women's gymnastics members, UC Davis, will join the Mountain West Conference, which sponsors that sport, in 2026.

Men's and women's indoor track & field were introduced for the 1992–93 season as one of the conference's inaugural sports.

Men's volleyball was introduced for the 1993 season (1992–93 school year) as one of the conference's inaugural sports.

The MPSF has won every men's and women's water polo NCAA title since the inception of the conference.