Vocalist Phil Anselmo stated in a 1992 interview on Much More Music, that "Mouth for War" is about channeling your hate into something productive.

[2] In 1993, iD Software composer Bobby Prince created a MIDI rendition of the song for use in their game Doom.

"Mouth for War" has been covered by Italian melodic death metal band Disarmonia Mundi on their third album, Mind Tricks.

An instrumental, all-cello version was recorded by The Portland Cello Project on the Kill Rock Stars label.

In March 2021, Lzzy Hale of Halestorm, Reba Meyers of Code Orange, Gina Gleason of Baroness, Madi Watkins of Year of the Knife, Ben Koller of All Pigs Must Die and Mutoid Man, and Jordan Olds (aka Gwarsenio Hall) collectively released a cover of the song on the "Two Minutes to Late Night" YouTube channel.