The Mrs. Osburn House is a historic home located in Durham, Greene County, New York.

It was built about 1850 and is a five-by-three-bay timber frame dwelling.

It features clapboard siding and a low-pitched hipped roof.

[2] It was listed on the National Register of Historic Places in 2001.

This article about a historic property or district in Greene County, New York, that is listed on the National Register of Historic Places, is a stub.