His comprehensive explanation of Sahih Muslim, titled Takmilah Fath al-Mulhim, spans six volumes and is considered his finest work.

Among his other works in the field of hadith sciences are Inamul Bari, Darus Tirmizi, and The Authority of Sunnah.

Muhammad Taqi Usmani was born on 5 Shawwal 1362 AH (3 October 1943) in the city of Deoband in Saharanpur district, United Provinces, British India.

The forefathers of Miyanji Shukr Allah are unknown, but the family claims descent from Uthman, the third caliph and a companion of the Islamic prophet Muhammad, hence the nisbat "Usmani".

After completing his primary education, he began his formal religious training in the Dars-i Nizami curriculum in 1953.

He then obtained his Takhassus (specialization) degree in fiqh (Islamic jurisprudence) and ifta (fatwa issuance) from Darul Uloom Karachi in 1961, earning the title of "Mufti".

In 1970 he obtained a Master of Arts with first-class honours in Arabic language and literature from the University of Punjab.

[citation needed] According to The Muslim 500: "Usmani's chief influence comes from his position as a global authority on the issue of Islamic finance.

"[12] He currently teaches Sahih al-Bukhari, fiqh, and Islamic economics at Darul Uloom Karachi and is known for his Islahi Khutbat.

He was a key member of a team of scholars which helped declare Ahmadis non-Muslims by Pakistan's National Assembly during the era of former Pakistani president, Zulfikar Ali Bhutto, in the 1970s.

[12] Usmani strongly opposes elements of explicit modernity, which he describes as engulfing "the whole world in the tornado of nudity and obscenity, and has provided an excuse for fornication, and more so it has led under thunder claps to the passage of a bill in the British House of Commons to legalize homosexuality.

It is in the shadow of the same modernity that Western women are openly displaying banners on the streets demanding legalization of abortion"[21]At a religious conference in 1984, he urged a more "dynamic attitude" towards the practice of ijtihad, arguing there is no shortage of fine minds capable of interpreting the sharia, but warning against the contamination of sharia by Western ideas such as the elimination of hudud penalties such as amputation and stoning.