He played in the Buffalo Rangers, New York Giants, Staten Island Stapletons, Green Bay Packers, and Portsmouth Spartans of the National Football League (NFL).

Wilson was the quarterback of the 1921 team that lost the state championship to Oak Cliff High School 7-0.

He became the first Texas state high school track champion (and the first Aggie) to play in the NFL.

He and Jacob Poth were the top Aggie sprinters and finished 1-2 in several dual meets.

Wilson was an All-SWC fullback in both 1924 and 1925 and “was noted for his great speed and power and his exceptional punting ability.” He was considered the best punter in the SWC.

Wilson went on to star for the Texas A&M Aggies, where he was a letterman both in football and in track for the years 1923 through 1925.

He only played with Buffalo for the 1926 season, then he signed with the New York Giants, and was on the 1927 NFL Championship team.

Wilson was the first Aggie in the NFL and won three world championships – one on the NY Giants and two with the Greenbay Packers.