MPD Psycho was adapted as a live action television miniseries in 2000, directed by Takashi Miike.

[2] Yôsuke hunts down the killer, but loses his sanity and developes dissociative identity disorder in the process, with the two main personalities being Kazuhiko Amamiya, a cool headed detective and Shinji Nishizono, a reckless psychopath.

[2] After being placed in prison for murdering the killer, Yôsuke Kobayashi is released and works for an independent detective agency ran by Machi Isono.

In exchange, Miwa demands that Tetora promise to keep the Kazuhiko personality alive and safe inside him no matter what.

Coincidentally, he sees Isono Miwa and decides to get on the same flight as her because he thought that "some interesting things would occur" and assists in the hijacking of the plane for his own purposes.

She employs Kazuhiko Amamiya upon his release from prison and invites him to live in the large apartment which serves as home to herself and her sister as well as the headquarters of her business.

Miwa Isono appears episodes five and six of the television series as a comatose girl rescued from a burning hospital who later forms a relationship with Amamiya.

Gakuso is a very secret, very influential and ruthless company with surprisingly high technology in the field of genetics, shrouded in mystery and sometimes confusing in its goals.

For some reason, one of the main projects of Gakuso seems to be recreating Lucy Monostone by mixing fragments of programmed personalities in a host body.

It is revealed in chapter 79 that the reason Gakuso does the barcode experiments is not just to make a perfect killer, but a controllable one who will serve to further their companies aims.

A pale-haired man who seems frequently involved with many serial killers, including Toguchi Kikuo, Nishizono Shinji (original) and Umemiya Akio.

He shows abnormal regenerative abilities (being able to completely regenerate his forearm) and wears earphone-like machines which can release endorphins to dull his sense of pain.

Lucy Monostone (ルーシー·モノストーン), a deceased former American pop star and terrorist, is thought by the mysterious corporation at the heart of the conspiracy to be the perfect killer.

Short tempered and easily confused, Sasayama is nevertheless a "straight arrow" and reliably on the side of the good guys.

Despite his duties to Onihigata, he seems sincerely interested in unraveling the mysteries behind the murders and promoting justice and safety.

He dies after a failed attempt to kill Onihigata, and ultimately donates his liver (unwillingly) to his would-be victim.

He is thought to be immortal by many characters as he seems to survive every attack made on him, including being run over by a car, and falling with a helicopter which explodes crashes into a tower when the pilot is shot.

He was in charge of keeping Nishizono Tetora under control by supplying him with medicines which must be taken in sequential order based on the numbers printed on the pills.

MPD Psycho was initially published in Shōnen Ace, moving to Comic Charge in 2007 and remaining there until the magazine was cancelled in 2009.

[8] Dark Horse Comics published the English translation, but put the series on indefinite hiatus after volume 9 was released.

Dark Horse announced in September 2010 it would resume MPD Psycho with the stabilization of the American manga market.

[12] Drawn by Hirarin The plot is similar to the beginning of the manga series but does not relate to the incidents of Lucy Monostone and the Gakuso Company.

Yôsuke Kobayashi, a detective assigned to a homicide unit, saw his wife killed by a serial killer, Shinji Nishizono.