Located in Census Division 17, the MD takes its name from Lesser Slave River, which drains Lesser Slave Lake into the Athabasca River.

The following urban municipalities are surrounded by the MD of Lesser Slave River No.

[3] The following hamlets are located within the MD of Lesser Slave River No.

In the 2021 Census of Population conducted by Statistics Canada, the MD of Lesser Slave River No.

[6] In the 2016 Census of Population conducted by Statistics Canada, the MD of Lesser Slave River No.