The series was created by Steven Bochco and Eric Lodal, and stars Taye Diggs and Kathleen Robertson.

[5] In the first season, Homicide Inspectors Terry English and Hildy Mulligan investigate two seemingly unrelated murders only to learn both victims have ties to a Silicon Valley prodigy who is darker than anyone realizes.

In the second season, as San Francisco recovers from a school bus massacre, English and Mulligan investigate the death of a fellow officer and uncover a conspiracy that shakes the city to its core.

In the third season, English and Mulligan juggle investigating a football player's murder and dealing with their respective personal issues while District Attorney Mario Siletti reels from a tragedy that jeopardizes his career.

"[13] Murder in the First has aired in several international countries in Italy, France, Australia, Latin America, Portugal, United Kingdom, Russia, Denmark, and Germany.