[2] After graduation from college she worked as an advertising copywriter for Sears Roebuck in New York, then as a publicist for Tom Jefferson & Associates in Miami, Florida, where she headed the Dade County re-election campaign of Senator Claude Pepper and helped elect Miami Mayor William M.
[2] She was described in Business Week Magazine's list of 100 Top Corporate Women in June 1976 as the "top-ranking woman in public relations.
[2] She also served as president of Byoir subsidiaries ByMedia (communications training) and ByMart (smaller accounts).
[2] In 1965–68, she and Senator Maurine Neuberger co-chaired then-vice president Hubert Humphrey's task force on Women's Goals.
[2] In 1966, she co-founded the National Organization for Women (NOW), and she was NOW president Betty Friedan's main lieutenant and director of operations in its earliest years.
[1][9] In 1975, she organized a successful meeting between NOW officers and Byoir client Sesame Street, which headed off a planned NOW boycott while also resulting in increased participation of female characters on the influential TV show.
By thus becoming aware of their counterparts in all fields, and of mutual interests and attitudes, they can, when desired, speak in concert on issues confronting the total community.
[15][16][17][18] In speeches she often urged successful women to abandon their old roles as "Queen Bee" in a man's world.
"[9] At the age of 94 she wrote The Women's Revolution: How We Changed Your Life, published by New Village Press, June 18, 2024.
[25] On October 21, 2014 Gloria Steinem presented her with the Lifetime Achievement Award of Veteran Feminists of America in a luncheon at the Harvard Club in Midtown Manhattan, featuring appearances by feminists Eve Ensler, Rosie O'Donnell, Marlo Thomas and Carol Jenkins.
[9] "Papers of NOW officer Muriel Fox, 1966–1971" is at the Arthur and Elizabeth Schlesinger Library on the History of Women in America, Radcliffe Institute for Advanced Study, Harvard University.