Murray Harbour is a community that holds rural municipality status in Prince Edward Island, Canada.

Located in the township of Lot 64, the community is named after General the Honourable James Murray, (1721–94), Governor of Quebec (1764–66).

It also hosts some secondary industry in the form of fish processing and a growing tertiary service economy centred on tourism.

The majority of the community's fishing fleet is berthed at the South River Harbour facility which is operated by Fisheries and Oceans Canada.

He wrote on June 3, 1806, that eight families (the Brehauts, Robertsons, Taudvins, Machons, Marquands, DeJerseys, and Sullivans) who had arrived on a ship from Guernsey on May 16, 1806, had gone to Murray Harbour.