The museum's collection and location have been housed since 1934, in the main wing of the Abbey of St. Bénigne, situated next door to the Dijon Cathedral.

[1] The museum first emerged as a collection created by a subdivision of the Academy of Dijon called the Commission des Antiquités du Département de la Côte-d'Or in 1832.

[1] Pilgrims from as far as the Mediterranean came to offer Sequana ex-votos at the source of the Seine River, with the temple to her being expanded by the Romans before its destruction in the fourth or fifth century AD.

"[1] The monks' dormitory exhibits Romanesque sculptures, including a bust of Jesus Christ wearing a crown of thorns sculpted by Claus Sluter.

The bust is a fragment of a larger limestone crucifix that was erected in the courtyard of the Carthusian monastery of Champmol in Dijon as part of Sluter's Well of Moses.