The Musée de l'Imprimerie (French pronunciation: [myze də lɛ̃pʁimʁi]) is a museum in Lyon, France, with the mission of enhancing, conserving, documenting and valuing the heritage of printed books and graphic arts.

[2] The Musee de l'Imprimerie was established in Lyon because Lyon had been a centre of printing and the book trade in Europe in the 15th and 16th centuries, and the city held large historical collections of books and the graphic arts.

The Museum of Printing and Graphic Communication experienced in 2014, on the occasion of its fiftieth anniversary,[5] several changes orchestrated by the then director Alan Marshall.

The museum has works by early printers of Lyon, including Martin Husz, Josse Bade, Sébastien Gryphe, Etienne Dolet, Jean de Tournes, Guillaume Rouillé and Bernard Salomon.

It includes displays of the 20th-century inventions, Higonnet and Moyroud's Lumitype-Photon phototypesetter and the BBR system of computer typesetting.