[2] His collections (zoology, botany, mineralogy) were first exhibited in his apartment, before being successively accommodated in the buildings of the Great Seminary (adjacent to the cathedral) and in the Krutenau neighbourhood.

It will allow the museum to reach current insulation, accessibility and security standards, and renew its permanent exhibition.

Exchanges and interpersonal relations allowed the successive directors to receive collections from the Paris National Museum of Natural History, as well as from the German scientific expeditions of the 1890s and 1900s.

Collections also include historical books and prints, as well as plaster and glass pedagogical models made by doctor Louis Auzoux and brothers Leopold and Rudolf Blaschka, respectively.

The museum holds specimens belonging to species that are rarely seen, like the coelacanth and night parrot, or declared extinct, such as the thylacine, great auk or passenger pigeon.