Musashi-Mizonokuchi Station (武蔵溝ノ口駅, Musashi-Mizonokuchi-eki) is a passenger railway station located in Takatsu-ku, Kawasaki, Kanagawa Prefecture, Japan, operated by East Japan Railway Company (JR East).

Musashi-Mizonokuchi Station is served by the Nambu Line, and is located 12.7 km (7.9 mi) from the terminus of the line at Kawasaki Station.

The station has a Midori no Madoguchi staffed ticket office.

Along with privatization and division of JNR, JR East started operating the station on 1 April 1987.

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